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Comparison of the Effects of Using Methylprednisolone in Cardiopulmonary Bypass Prime Solution on Hemogram and Biochemistry Values with Unused Cases
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Research Article
VOLUME: 1 ISSUE: 1
P: 8-14
April 2023

Comparison of the Effects of Using Methylprednisolone in Cardiopulmonary Bypass Prime Solution on Hemogram and Biochemistry Values with Unused Cases

Turk J Clin Cardiov Perfusion 2023;1(1):8-14
DOI: 10.4274/tjccp.galenos.2023.43434
Muhammet Candan 1
Tülay Candan 2
Korhan Erkanlı 3
Berra Zümrüt Tan Recep 4
1. Sağlık Bilimleri Üniversitesi, Başakşehir Çam ve Sakura Şehir Hastanesi, Kalp ve Damar Cerrahisi Kliniği, Perfüzyon Birimi, İstanbul, Türkiye
2. Sağlık Bilimleri Üniversitesi, Mehmet Akif Ersoy Göğüs Kalp ve Damar Cerrahisi Eğitim ve Araştırma Hastanesi, Kalp ve Damar Cerrahisi Kliniği, Perfüzyon Birimi, İstanbul, Türkiye
3. Medipol Mega Üniversite Hastanesi, Kalp ve Damar Cerrahisi Kliniği, İstanbul, Türkiye
4. Sağlık Bilimleri Üniversitesi, Başakşehir Çam ve Sakura Şehir Hastanesi, Çocuk Kalp ve Damar Cerrahisi Kliniği, İstanbul, Türkiye
No information available.
No information available
Received Date: 04.03.2023
Accepted Date: 29.03.2023
Publish Date: 25.04.2023
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ABSTRACT

Objective:

In the first periods of cardiac surgery, blood was added to the prime solution. Balanced electrolyte solutions were started to be used since it was difficult to find blood in long-lasting heart surgery cases. Thus, in hospitals, there was the need for blood a decrease in. It is also easier to prepare the bypass system in emergency cases.

Materials and Methods:

In this study, a total of 40 patients, including 20 patients without methyprednisolone (group A) and 20 patients with methylprednisolone added (group B) to included in the cardiopulmonary bypass (CPB) prime solution. As a parameter of hemogram erythrocyte distribution width-standard deviation (RDW-SD), glucose, lymphocyte, leukocyte, hematocrit (HCT), platelet (PLT), and postoperatively routinely controlled data were compared and evaluated.

Results:

There was no statistically significant difference between lymphocyte, leukocyte, RDW-SD, leukocyte, HCT, PLT values and the stay of intensive care unite, intubation time and drainage amount (p>0.05). Hospital stay in group B cases was shorter than in group A cases (p<0.018). A significant difference was found between the groups in terms of both preoperative and postoperative mean glucose values (p<0.001). Postoperative blood glucose values were found to be higher and statistically significant in group B patients, especially those using methylprednisolone (p<0.001).

Conclusion:

As a result of this study, it was concluded that patients who were applied non-pulsatile flow during CPB had more beneficial effects than patients who did not add methylprednisolone to prime solution.

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