Abstract
Objective
Cardiopulmonary bypass (CPB), an essential component of cardiac surgery, is continuously evaluated regarding the advantages and disadvantages of perfusion techniques. The effects of shorter or prolonged perfusion durations on patient outcomes have been widely discussed. This study aimed to evaluate the impact of perfusion duration on hospital length of stay.
Materials and Methods
In this retrospective study, patients who underwent coronary artery bypass grafting (CABG) among open-heart surgeries performed at University of Health Sciences Türkiye, Koşuyolu High Specialization Training and Research Hospital between January 2019 and December 2020 were evaluated. Patients were divided into two groups according to CPB duration: <100 minutes and >100 minutes. Demographic characteristics, hematological and biochemical parameters, intensive care unit (ICU) stay, and total hospital length of stay were analyzed to assess the relationship between CPB duration and hospitalization time.
Results
Prolonged CPB duration was associated with significantly longer ICU and hospital stays and higher postoperative urea, creatinine, and aspartate aminotransferase levels. Demographic characteristics, ejection fraction, most hematologic parameters, alanine aminotransferase levels, and extubation times showed no significant differences between groups, indicating that longer CPB duration may adversely affect postoperative recovery and hospitalization.
Conclusion
In this study, the effect of CPB duration on hospital discharge time in patients undergoing CABG was evaluated. Previous studies have shown that many adverse effects associated with CPB are related to the duration of bypass. Prolonged CPB time has been linked to systemic inflammatory response, organ dysfunction, and increased postoperative complications, which may lead to longer ICU and hospital stays. Our findings suggest that longer CPB durations may negatively affect discharge time. Therefore, maintaining the shortest possible bypass duration while ensuring surgical safety is important. Minimizing unnecessary delays during surgical and perfusion procedures may contribute to improved postoperative recovery. Further studies with larger patient populations are required to obtain more robust and generalizable results.
Keywords:
CPB, perfusion, coronary artery bypass grafting, intensive care unit length of stay, hospital length of stay
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