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Preoperative-postoperative Comparison of Lung Pressures in Patients Treated with MUF
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Research Article
VOLUME: 1 ISSUE: 3
P: 101-110
December 2023

Preoperative-postoperative Comparison of Lung Pressures in Patients Treated with MUF

Turk J Clin Cardiov Perfusion 2023;1(3):101-110
DOI: 10.4274/tjccp.galenos.2023.63825
Zeynep Averbek Arslan
Ali Kocailik
1. Sağlık Bilimleri Üniversitesi, Başakşehir Çam ve Sakura Şehir Hastanesi, Perfüzyon Birimi, İstanbul, Türkiye
No information available.
No information available
Received Date: 06.09.2023
Accepted Date: 12.11.2023
Publish Date: 29.12.2023
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ABSTRACT

Objective:

Elliot et al. in 1993, and Rivera et al. in 1998 showed an increase in systolic blood pressure in patients who underwent modified ultrafiltration (MUF) in their studies (50). In our study, a significant increase was found in the arterial pressure values at the 8th hour of the intensive care unit (ICU) compared to the pre-CPB (p=0.003; p<0.01).

Materials and Methods:

In our study, 50 patients in the 0-1 age group diagnosed with Arcus hypoplasia who underwent Arcus reconstruction were retrospectively analyzed. Before and after CPB, blood gas parameters, airway pressure, tidal volume, and end-expiratory positive pressure (PEEP) data were examined. Blood products taken before and during CPB, amount of urine, cerebral and renal NIRS, blood gas parameters were examined. ICU 8th hour blood gas parameters, airway pressure, tidal volume, and PEEP values were examined (Ethics Committee-Üsküdar University Non-Interventional Clinical Research Ethics Committee Form, number: 2023-47, date: 28.11.2022).

Results:

In this study, we aimed to observe the change in airway pressure (PAW) in the lungs of MUF. It was determined that the PAW values of the patients were lower after MUF than before MUF, and the difference was statistically significant (p=0.001; p<0.01). An increase in Hb and Htc values was observed after MUF compared to before MUF, and a statistically significant difference was observed (p=0.001; p<0.01). Potassium, lactate, renal NIRS and PAW values were decreased and statistically significant difference was found (p=0.001; p<0.01).

In this study, it was concluded that MUF applied after CPB decreased the PAW, lactate, and potassium in the lungs and significantly increased the hemoglobin and Htc values (p=0.001; p<0.01).

Conclusion:

As a result of our study, we can say that since MUF reduces the PAW in the lungs, it has positive effects on shortening the extubation time of the patients and consequently shortening the length of stay in the ICU.

References

1
Larmann J, Theilmeier G. Inflammatory response to cardiac surgery: cardiopulmonary bypass versus non-cardiopulmonary bypass surgery. Best Pract Res Clin Anaesthesiol 2004;18(3):425-438.
2
Naik SK, Elliott MJ. Ultrafiltration and paediatric cardiopulmonary bypass. Perfusion 1993;8(1):101-112.
3
Boodhwani M, Hamilton A, de Varennes B, Mesana T, Williams K, Wells GA, et al. A multicenter randomized controlled trial to assess the feasibility of testing modified ultrafiltration as a blood conservation technology in cardiac surgery. J Thorac Cardiovasc Surg 2010;139(3):701-706.
4
Magilligan DJ Jr, Oyama C. Ultrafiltration during cardiopulmonary bypass: laboratory evaluation and initial clinical experience. Ann Thorac Surg 1984;37(1):33-39.
5
Raja SG, Yousufuddin S, Rasool F, Nubi A, Danton M, Pollock J. Impact of modified ultrafiltration on morbidity after pediatric cardiac surgery. Asian Cardiovasc Thorac Ann 2006;14(4):341-350.
6
Bando K, Turrentine MW, Vijay P, Sharp TG, Sekine Y, Lalone BJ, et al Effect of modified ultrafiltration in high-risk patients undergoing operations for congenital heart disease. Ann Thorac Surg 1998;66(3):821-7; discussion 828.
7
Kopman EA, Ferguson TB. Pulmonary edema following cardiopulmonary bypass. Anesth Analg 1978;57(3):367-371.
8
Chaturvedi RR, Shore DF, White PA, Scallan MH, Gothard JW, Redington AN, et al. Modified ultrafiltration improves global left ventricular systolic function after open-heart surgery in infants and children. Eur J Cardiothorac Surg 1999;15(6):742-746.
9
Davies MJ, Nguyen K, Gaynor JW, Elliott MJ. Modified ultrafiltration improves left ventricular systolic function in infants after cardiopulmonary bypass. J Thorac Cardiovasc Surg 1998;115(2):361-369; discussion 369-370.
10
Kameyama T, Ando F, Okamoto F, Hanada M, Yamanaka K, Sasahashi N, et al. The effect of modified ultrafiltration in pediatric open heart surgery. Ann Thorac Cardiovasc Surg 2000;6(1):19-26.
11
Naik SK, Elliott MJ. Ultrafiltration and pediatric cardiopulmonary bypass. Cardiology in the Young 1993;3(4):331-339.
12
López R, Lema G, González A, Carvajal C, Canessa R, Carrasco P, et al. Plasma levels of potassium and magnessium after modified ultrafiltration in pediatric cardiac surgery with cardiopulmonary bypass. Perfusion 2012;27(1):40-42.