ABSTRACT
During cardiopulmonary bypass (CPB) and in the postoperative period, high lactatemia is a common condition. Lactate increases in anaerobic energy metabolism because of low tissue oxygenation or disturbances in tissue circulation. The aim of this study was to investigate the effects of CPB hypothermia and normothermia on lactate and pH levels.
The patients were divided into hypothermic group 1 (n=35) and normothermic group 2 (n=35) during CPB. The two groups were compared in terms of preoperative, peroperative, and postoperative biochemical values, ejection fraction changes, inotrope use and dose, intensive care unit length of stay, and extubation times.
There was no statistically significant difference between the groups in terms of pre-CPB, post-CPB and postoperative 24th hour pH values (p>0.05). There was a statistically significant difference in postoperative pH values between the groups (Z=-2.391; p=0.017). There was no statistically significant difference between the groups in terms of pre-CPB and post-CPB lactate values (p>0.05). There was a statistically significant difference between the groups in terms of 24 h lactate values (Z=-1.962; p=0.049).
The results suggest that maintaining normothermia may favorably affect postoperative lactate and pH levels.