ABSTRACT
Objective:
The relationship between serum uric acid level and pump duration and acute kidney injury (AKI) in cardiac surgery is highly effective on mortality, morbidity and hospital stay. It is important to consider preoperative uric acid and pump time in early detection and risk stratification of AKI. From this point of view, in this study, it is aimed to examine the effect of perfusion time on the development of AKI in patients with high preoperative serum uric acid levels.
Materials and Methods:
In this retrospective study, 104 patients were examined between January and December 2017, after obtaining the necessary permission from University of Health Sciences Turkey, Kartal Koşuyolu Yüksek İhtisas Training and Research Hospital. First group (n=67) patients with a pump duration of 100 minutes or more 2. group (n=37) patients with pump time less than 100 minutes were included.
Results:
In this study, 26.9% of the patients in group 1 with a pump time of 100 minutes and ↑ developed AKI, 73.1% of them did not, and 8.1% of the patients in group 2 with a pump time of 100 minutes ↓ it was determined that AKI developed in 91.9% of the patients and it did not develop in 91.9% of them, and it was found to be significant (p<0.05).
Conclusion:
In patients with high uric acid in the preoperative period, it was determined that the pump duration of 100 minutes and ↑ had a statistically significant effect on the development of AKI andit was more risky in terms of AKI. In addition, in our study, it was determined that the prolongation of the aortic cross clamp time is among the factors that cause the development of AKI. Before open heart surgery, it is important to pay attention to the pump and aortic cross clamp duration and to take precautions accordingly in patients with a serum uric acid value above 6 mg/dL.
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