ABSTRACT

Objective:

One of the most important issues to achieve successful clinical outcomes in open heart surgery is to prevent organ reperfusion injury. Currently, acute and chronic renal failure in patients undergoing cardiac surgery greatly affects postoperative morbidity and mortality. In this study, the effects of aortic clamping time on renal functions in patients undergoing valve surgery were investigated.

Materials and Methods:

This study was analysed in a total of 50 patients who underwent open heart surgery at İstanbul Medipol Mega University Hospital, including patients with cross clamp duration less than 90 minutes (group 1) (n=25) and over 90 minutes (group 2) (n=25). Renal flow-related glomerular filtration rate and creatinine values of the two groups were compared preoperatively and postoperatively within and between the groups.

Results:

A statistically significant difference was found in terms of pump time (min), pump urine (mL/hour), intubation time (hour) and intensive care unit (ICU) hospitalisation time (hour) according to cross time classes (p<0.05). The pump time (min), pump urine amount (mL/hour), intubation time (hour) and ICU stay time (hour) of those with a cross time >90 min were significantly higher than those with a cross time <90 min. A positive, moderate and statistically significant correlation was found between pump duration and urine volume in those with a cross duration <90 min (r=0.536; p=0.006).

Conclusion:

As a result of the study, it was determined that increased pump duration negatively affected diuresis and was associated with other adverse clinical outcomes.

Keywords: Cardiopulmonary bypass, aortic clamp duration, renal dysfunction

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Effect of Cross Clamp Duration on GFR and Creatinine Values Due to Renal Flow in Valve Patients Undergoing Open Heart Surgery

ABSTRACT

References